Understanding Your Options
When you're struggling with infertility, your doctor will likely discuss two main treatment paths: intrauterine insemination (IUI) and in vitro fertilization (IVF). Both have helped millions of families, but they work very differently.
What Is IUI?
IUI is a simpler, less invasive procedure where specially prepared sperm is placed directly into the uterus around the time of ovulation. It's often the first fertility treatment recommended because it's less expensive and less physically demanding than IVF.
What Is IVF?
IVF is a more complex process where eggs are retrieved from the ovaries, fertilized with sperm in a laboratory, and the resulting embryo(s) are transferred back into the uterus. It involves hormone injections, regular monitoring, an egg retrieval procedure, and an embryo transfer.
Success Rates Compared
IUI success rates: 10-20% per cycle for women under 35, dropping to 5-10% for women over 40.
IVF success rates: 40-50% per cycle for women under 35, 25-35% for ages 35-37, 15-25% for ages 38-40.
Cost Comparison
IUI: $500-$4,000 per cycle (including medications and monitoring)
IVF: $12,000-$25,000 per cycle (including medications)
While IVF costs more per cycle, its higher success rate means fewer cycles are often needed.
When IUI Is Recommended
IUI may be the right choice if you have unexplained infertility, mild male factor infertility, cervical factor infertility, or if you're using donor sperm. It's also appropriate when at least one fallopian tube is open and the woman is under 38.
When IVF Is Recommended
IVF is typically recommended for blocked or damaged fallopian tubes, severe male factor infertility, advanced maternal age (over 38), failed IUI cycles, endometriosis, or when genetic testing of embryos is needed.
Making Your Decision
Talk to your reproductive endocrinologist about your specific diagnosis, age, and goals. Use our directory to find a fertility specialist near you for a personalized consultation.